The ecological space of Chengdu-Chongqing Twin Cities Economic Circle is an important part of ecological civilization construction in southwest China. Taking the ecological space of Shuangcheng economic circle in Chengdu-Chongqing region as the research object, based on the theories of composite ecosystem, integrated protection and management of mountains, water forests, fields, lakes, grass and sand, this study comprehensively selected evaluation indicators from the aspects of policy objectives and public demand, used the coefficient of variation method and judgment matrix method to carry out ecological spatial zoning and proposes corresponding control mechanisms. The results showed that: (1) ESQ showed a stable and positive trend in the past 10 years, with a "basin-type" distribution pattern of low central space and high four weeks, and the quality grade change showed the characteristics of "good in the middle and stable in all around", mainly unchanged and improving; (2) ESQ was between weak variation and medium variation, and the proportion of weak variation area was large, and ESQ was relatively stable as a whole; (3) Based on the analysis of quality change characteristics and stability, the ecological space was divided into key protected areas, potential restoration areas, key restoration areas and ecological conservation areas. Implemented original ecological protection in key protected areas, and carryed out closed nature conservation; the key restoration areas were mainly artificial ecosystems, focusing on the implementation of artificial restoration, and carrying out ecological restoration and treatment projects; potential restoration areas should give priority to protection, focused on natural restoration, and strive to improve the overall ecological state; ecological conservation area was the main type of ecological space in the research area, ecological conservation should be implemented, on the basis of ecological protection, production development and construction could be reasonably carried out, and this area could provide strategic direction for the future urban development of the research area and reserve space for development. The study of zoning management and control of ecological space can facilitate decision-makers to identify and manage ecological protection and restoration space, and provide new ideas for the future development direction of the Chengdu-Chongqing Twin Cities Economic Circle.