The objective of this study was to explore the effect of different film hole diameters on the characteristics of multi-point interference infiltration wetting body, a testing program of laboratory experiment with four different film hole diameters was designed, the changes in the characteristics of the wetting body with time under different film hole diameters were measured. The results showed that at the same time, the larger the film hole diameters, the greater the horizontal and vertical wetting front transport distance. The power function model was suitable for characterizing the relationship between the horizontal and vertical wetting front transport distance on the free infiltration surface and the time of infiltration. As the diameter of the film hole increased, the transport parameters gradually increased and the transport indexes gradually decreased. The relationship between the horizontal and vertical wetting front transport distance and the infiltration time were logarithmic function model on the intersection profile. As the diameter of the film hole increased, the soil moisture content around the film hole was close to the saturated, and the soil moisture content at the same locationincreased, and the time of unidirectional and multidirectional interference to occur gradually decreased. The irrigation uniformity coefficient in the wetting body of muddy water with film hole irrigation was greater than 90%, and the irrigation uniformity was very high.