In this study, the effects of different organic materials on the salinity and dissolved organic carbon (DOC) of leachate and the salinity, organic matter and microbial carbon and nitrogen in different depths of soil were studied by soil column simulation test, including five different treatments: organic silicon functional fertilizer (WO), particle organic materials (YP), powder organic materials (GG), 50% particle organic materials and 50% powder organic materials mixed respectively (YG) and no organic materials (CK). The results showed that the addition of organic materials increased the EC value and water-soluble Ca²⁺, Mg²⁺ and Na⁺ concentration in the leachate. The contents of salt ions leached by YP treatment were the highest, but the content of DOC in the leachate treated by WO was the lowest. Compared with CK treatment, WO treatment significantly increased the water-soluble Ca²⁺, Mg²⁺ and K⁺ contents in each depth of soil layer, significantly reduced the pH, exchangeable Na⁺, exchangeable solium percentage (ESP) in each depth of soil layer, and water-soluble Na⁺, sodium absorption ratio (SAR) in 0—20 cm soil layer, but there was no significant difference in pH, EC and salinity between other organic materials and CK treatment. Leaching moved the soil salt from the surface (0—20 cm) to the deeper layers. After leaching, EC value, water-soluble total salt, exchangeable Na⁺ and ESP increased with the increase of soil depth. Compared with CK treatment, GG and YG treatment significantly increased the content of organic matter in 0—20 cm soil layer by 23.97% and 20.53%, respectively. These results could provide a theoretical data reference for the changes of salt and organic matter in the process of saline-alkali soil leaching with the addition of organic materials.