In order to alleviate the serious soil and water loss of slope in Hilly-Gully Loess Region, this paper took DuanLanyao drainage loess slope in Qingshuihe County of Inner Mongolia as the research area, and adopted three vegetation carpet measures:the mixed planting of Legumes and Gramineae plants with a ratio of 1:1+coconut carpet (L₁G₁), the mixed planting ratio of 1:2 + coconut carpet (L₁G₂), and the ratio of 2:1 + coconut carpet (L₂G₁). Runoff plots were set up with slope gradients of 30°, 35°, 40° and 45°. The effects of different natural rainfall conditions and slopes on slope runoff and sediment yield were analyzed. The results showed that:(1) Vegetation carpet could effectively reduce the runoff and sediment yield of Loess slope. (2) When the rainfall intensity was 1~5 mm/h, the runoff and sediment yield of vegetation carpet measures increased with the increase of slope gradients; when the rainfall intensity was 30~50 mm/h, the runoff and sediment yield of vegetation carpet measures increased first and then decreased with the increase of slope gradients, and the peak value appeared when the slope was 40°. (3) The benefits of three vegetation carpet measures were L₁G₁ (75.11%) > L₁G₂ (49.3%) > L₂G₁ (48.11%) and L₁G₁ (87.96%) > L₁G₂ (60.96%) > L₂G₁ (58.95%), respectively. It could be concluded that L₁G₁ was an effective measure to control soil and water loss of slope in the Hilly-Gully Loess Region.