Conducting landslide susceptibility analysis is the foundation for formulating reasonable geological disaster prevention and control plan, which is of great significance for disaster prevention and reduction. Taking Nujiang Prefecture as the research area and slope unit as the evaluation unit, nine factors including elevation, slope, slope aspect, NDVI, rainfall, lithology, distance from fault and distance from road were selected as evaluation factors. Information content (I) model, deterministic coefficient (CF) model and I-LR and CF-LR coupling models were used to evaluate landslide susceptibility. The accuracy of the four models was verified. The results showed that:(1) In the CF-LR model, the proportion of landslide points falling into high and extremely high prone areas was the largest, accounting for 88.77%, the density of landslide points (0.309 2) was the largest, which was higher than that of I model (0.285 4) and CF model (0.277 6). (2) The extremely high and highly prone areas mainly developed in the Nujiang River, Dulong River, Lancang River and Tongdian River. The middle prone area was mainly distributed in the eastern part of the study area. The low and very low susceptibility prone area was mainly distributed in the northern, central and western edge of the study area. (3) According to the results based on Sridevi Jadi empirical probability method and ROC curve, the prediction accuracy of CF-LR model was higher than that of the other three models.