Plant based sand fixing agents are environmentally friendly sand fixing agents mainly composed of plant material extracts. The feasibility of their application in sandy farmland was studied. Three plant-based sand fixing agents (Robinia pseudoacacia type, flax type, and sunflower type) and sandy soil were used as the research objects, and the same amount of water was sprayed as CK. Comparative experimental studies were conducted on the effects of different dosages on the formation of a consolidated layer of sand, compression resistance, wind erosion resistance, plant seed germination, and seedling growth. The results showed that:(1) When sprayed with black locust type, flax type, and sunflower type sand fixing agents on the surface of sandy soil, a consolidation layer with a thickness of 1 to 14 mm can be formed, and its average compressive strength is 206.21%, 147.51%, and 72.74% higher than CK. (2) All three plant-based sand fixation agents had significant sand fixation effects. As the dosage increases, the soil's resistance to wind erosion was significantly enhanced. At a dosage of 5 g/m², the wind erosion amount was the lowest, with a decrease of 65.92%, 58.33%, and 69.55% compared to CK, respectively; (3) Black locust type and flax type sand fixing agents had a promoting effect on wheat seed germination and bud growth, while sunflower type sand fixing agents had an inhibitory effect, and the inhibitory effect was obvious with increasing dosage. When the dosage reached 3 g/m², seed germination was significantly inhibited, and the germination rate was reduced by 62.50% compared to CK; When the dosage reached 4 g/m², root sprouting was significantly inhibited; When the dosage reached 2 g/m², the growth of buds was significantly inhibited. (4) The consolidation layer had a certain impact on the soil breaking of seedlings, with the black locust type sand fixing agent had the greatest impact. When the dosage reached 5 g/m², the emergence rate of wheat and alfalfa significantly decreased by 10.54% and 3.90% compared to CK. However, after the seedlings break through the consolidation layer, all three sand fixing agents had a certain promoting effect on the growth of wheat and alfalfa plants. Taking into account factors such as compressive strength, plant seed germination, and seedling growth, it has a good wind erosion resistance effect and no inhibitory effect on plants at the dosage of C3, C4, Y3, and Y4. This study provides a theoretical basis for the research and application of plant resource-based sand fixing agents, and provides a reference for the technology of wind erosion control of farmland soil.