In order to understand the influence of reclamation on the soil physical and chemical properties of alpine-cold grassland in northwest Sichuan, the method of replacing the time with the space was applied, and the vegetable lands in the alpine grassland which had been reclaimed for three and ten years were chosen as the research objects. In addition, the uncultivated natural grassland was taken as the control group to study the changing characteristics of the physical and chemical properties of 0—60 cm soil layers of different land reclamation years. The results showed that the artificial cultivation led to significant reduction in soil nutrient content, soil physical and chemical properties of natural alpine meadow, and the soil quality further decreased with the increase of reclamation years. After ten years of reclamation, soil bulk density and sand content in the 0—60 cm soil layer were increased by 21.1% and 8.0%, respectively; soil moisture, organic matter, total nitrogen, available nitrogen, and clay contents were decreased by 38.4%, 44.1%, 39%, 47.1%, and 19.2% respectively. Soil physical and chemical properties, and soil carbon and nitrogen contents were decreased most significantly in the surface layer (0—20 cm). With increasing soil depth, soil physical and chemical properties were weakened. The losses of soil carbon and nitrogen in the 0—20 cm soil layer occurred in the first three years of reclamation, while soil carbon and nitrogen in deeper layers (20—40 cm, and 40—60 cm) were not significantly lost in first three years of the reclamation. Losses of soil carbon and nitrogen mainly occurred in the first three to ten years of reclamation.