A soil column experiment was conducted to investigate leaching regimes of nitrogen (N) and phos- phorus (P) from four fertilizers,i.e.,organic compound fertilizer,inorganic compound fertilizer,pig ma- nure compost and peanut cake applied individually and in combination in latosolic red soils of South China. Results showed that leaching loss rates of fertilizer N ranged from 43.2% to 74.8% and those of fertilizer P ranged from 0.01% to 0.08%,exhibiting severe leaching loss of N and marginal leaching loss of P in latosol- ic red soils in South China.Leaching loss amounts of inorganic N were similar to those of organic N in the treatments where fertilizer was individually applied,but higher than those of organic N in the treatments where fertilizers were applied in couple.Particulate P (PP) was the main form of phosphorus leaching loss in all the treatments.The combined application of two fertilizers increased leaching loss amounts of ammonium and inorganic N,but at the same time reduced organic and total N leaching loss amounts.When pig manure compost was applied together with compound fertilizer,PP and total P (TP) leaching losses were reduced, but when peanut cake was applied with compound fertilizer,the leaching losses of PP and TP were elevated. Dissolved P (DP) leaching was reduced in all the combined fertilization treatments.Significant interaction effects of combined fertilization were found on leaching losses of N and P in latosolic red soils.