Use GIS and RS, analysis the TM images in 1994 and 1998 about Minqin County. The result show: somewhere in Minqin county desertification has been controlled, the same time somewhere been exacerbated. Around the Minqin oasis desert control is successes, the area of shrub become bigger. But beyond the oasis, the area of sandy grassland and salt grassland have been reduced 13.8% and 0.3%, the flow dune increased 0.3%. The reason of desertification is irrationality use water resource, overly graze on the grassland and overly bring under cultivation around the oasis. In the model area, Xishawo of Minqin, locates the tile of badanjiling desert and before Minqin oasis, after some years control, the land, and the forest are stable increased, the desertification in model area has been reversed. In the future, along with the fall of ground water, the degeneration of vegetation should be the major exhibition of desertification in Minqin County. We provide some advice for the control of desertification in Minqin County.