Grassland desertification is one of the most serious ecological and environmental problems in Qinghai-Tibet Plateau. To investigate the characteristics of vegetation and soil under different restoration measures in alpine desertification grassland, desertification grassland (DG), artificial herbage grassland (AG), artificial shrub grassland (AS) and natural grassland (NG) were selected to study the changes of vegetation community and soil characteristics and their relationship, and to evaluate the restoration effect of different artificial vegetation restoration measures on alpine desertification grassland after 22-year restoration. The results showed that:(1) AG and AS increased the aboveground biomass of desertification grassland to 109.21 and 1 293.21 g/m², respectively. However, the aboveground biomass of herbs under AG and AS were significantly lower than that of NG, and the species richness of AG was significantly lower than that of AS by 31.48% (p<0.05). (2) Compared with the 0-10 cm surface soil of DG, the soil porosity, water content, total carbon and total nitrogen contents of AG significantly increased by 7.94%, 67.95%, 22.09% and 257.14%, respectively. And these indexes of AS significantly increased by 6.41%, 43.00%, 17.18% and 242.86%, respectively. However, the content of soil carbon and nitrogen in the two restoration measures were significantly lower than that of NG (p<0.05). (3) The total accumulation of soil organic carbon mineralization in AS andAG was significantly higher than that in DG by 133.39% and 116.96%, respectively, but both were significantly lower than that in NG, and there was no significant difference between the two restoration measures (p>0.05). Therefore, artificial vegetation restoration measures significantly promoted vegetation and soil restoration in desertification grassland, but shrub restoration was more conducive to improve the species richness of vegetation communities, while herb restoration was more conducive to increase soil moisture of desertification grasslands.